See important information below about the risk of hepatitis B virus reactivation.

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Starting hep C treatment is just the beginning

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Your plan of action

Now that you and your health care provider have decided to start treatment for your hep C, it's time to make a commitment to yourself. It's important to follow your treatment plan in order to give yourself the best chance of curing your hep C. Cure means the hep C virus is not detected in the blood when measured 3 months after treatment is completed.

How to take ZEPATIER

1
PILL, ONCE A DAY WITH OR WITHOUT FOOD

Most people will take ZEPATIER for 12 weeks, one pill, once a day. Some people may take ZEPATIER plus another medicine called ribavirin, and some may take ZEPATIER plus ribavirin for 16 weeks. Your specific treatment plan depends on your hepatitis C (hep C) genotype, if you were treated for hep C in the past, and if there are certain rare changes to your hep C virus. Your health care provider will decide the treatment course that is right for you.

Do not stop taking ZEPATIER without talking to your health care provider.

If you take ZEPATIER with ribavirin, be sure you read the Medication Guide for ribavirin.

Download the C2Day™ mobile app for support during hepatitis C treatment and beyond

C2Day™ Mobile App

Manage your hep C on the go. The C2Day™ app helps you stay on track before, during, and after your treatment journey. You can:

  • Set up automatic reminders for your hep C and other medicines

  • Keep track of your daily activities

  • Connect with people just like you

  • Join weekly challenges to help you create healthy habits

  • Get tips to help put you on the path to a healthier you

  • Learn how to make smarter food choices

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Staying on track

Here's a list of tips that can help you remember when to take your medicine:

 

Take your medicine at the same time every day

Take your medicine every day at the same time as you do something else—like at meal time.

 

Make reminder notes

Put a reminder note on your refrigerator, medicine cabinet, or bathroom mirror.

 

Set an alarm

Set up an alarm on your phone or computer.

Your ZEPATIER pill should be taken once each day. It is important that you do not miss or skip doses of ZEPATIER. If you miss your daily dose, call your health care provider or pharmacist. Do not just take 2 doses at the same time to make up for the 1 you missed.

Take ZEPATIER exactly as your health care provider tells you to take it. Do not stop taking ZEPATIER without first talking to your health care provider. If you take more than your prescribed dose, call your health care provider right away.

Choose a healthy lifestyle

Keep a healthy diet:
Include foods from all the food groups.

  Grains
  Protein
  Fruits
  Dairy
  Vegetables
  Fats
 

Avoid alcohol

Alcohol can damage your liver and cause scarring.

Physical activity while on treatment for hepatitis C

Physical activity

Physical activity is important as well. If you're not already exercising regularly, try starting with 10-minute blocks of exercise, and slowly increase to get to about 15 to 30 minutes, 3 to 5 days a week.

Be sure to ask your health care provider before making any changes to your diet or exercise plan.

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Working together with your
health care provider

Tell your health care provider about all other medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. ZEPATIER may affect the way other medicines work, and other medicines may affect how ZEPATIER works. Some medicines cannot be taken with ZEPATIER.

Not sure what questions to ask at your next appointment?

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Have questions about getting access to ZEPATIER?

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What is ZEPATIER?

ZEPATIER® (elbasvir and grazoprevir) is a prescription medicine used to treat chronic (long‑lasting) hepatitis C (hep C) genotypes 1 or 4 infection in adults. ZEPATIER may sometimes be given with another medicine called ribavirin.

Important Safety Information

Before starting treatment with ZEPATIER® (elbasvir and grazoprevir), your health care provider will do blood tests to check for hepatitis B virus infection. If you have ever had hepatitis B virus infection, the hepatitis B virus could become active again during or after treatment of hep C virus infection with ZEPATIER. This is called hepatitis B virus reactivation, and it may cause serious liver problems including liver failure and death. Your health care provider will monitor you if you are at risk for hepatitis B virus reactivation during treatment and after you stop taking ZEPATIER.

ZEPATIER is not for people with certain liver problems. Before taking ZEPATIER, tell your health care provider about all of your medical conditions, including if you have ever had hepatitis B virus infection or have liver problems other than hep C. Also tell your health care provider if you have ever taken any medicine for hep C, have HIV, or have had or are waiting for a liver transplant.

If you are nursing, pregnant, or trying to get pregnant, tell your health care provider. It is not known if ZEPATIER® (elbasvir and grazoprevir) will harm your unborn baby or pass to your baby through breast milk. If you take ZEPATIER with ribavirin, be sure you read the Medication Guide for ribavirin, especially the important pregnancy, contraception, and infertility information.

Tell your health care provider about all of the medicines you take. ZEPATIER may affect how other medicines work, and other medicines may affect how ZEPATIER works. Some medicines cannot be taken with ZEPATIER. Your health care provider can tell you if it is safe to take ZEPATIER with other medicines.

ZEPATIER may cause increases in your liver-related blood tests, which could be a sign of serious liver problems. Your health care provider will do blood tests to check your liver before and during treatment with ZEPATIER. Tell your health care provider right away if you get any of the following symptoms or if they get worse during treatment with ZEPATIER: loss of appetite, nausea and vomiting, feeling tired or weak, yellowing of your skin or eyes, or color changes in your stool.

In clinical studies, common side effects of ZEPATIER included: feeling tired, headache, and nausea. When ZEPATIER was taken with ribavirin, common side effects also included low red blood cell counts (called anemia).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

Before taking ZEPATIER® (elbasvir and grazoprevir), please read the accompanying Patient Information, including information about the risk of the hepatitis B virus (HBV) becoming active again in patients who have ever had HBV infection, and discuss it with your doctor. The Prescribing Information also is available.

Questions about ZEPATIER?
Call 844-ZEPATIER (844‑937‑2843)
for more information.




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