ZEPATIER is a prescription medicine used with or without ribavirin to treat chronic (long-lasting) hepatitis C virus (HCV) genotypes 1 or 4 infection in adults.
Important Safety Information
ZEPATIER is not for people with certain liver problems. Tell your health care provider if you have liver problems other than hep C. Also tell your health care provider if you have ever taken any medicine for hep C, have HIV or any other medical conditions, or have had or are waiting for a liver transplant.
If you are nursing, pregnant, or trying to get pregnant, tell your health care provider. It is not known if ZEPATIER will harm your unborn baby or pass to your baby through breast milk.
Tell your health care provider about all of the medicines you take. ZEPATIER may affect how other medicines work, and other medicines may affect how ZEPATIER works. Some medicines cannot be taken with ZEPATIER. Your health care provider can tell you if it is safe to take ZEPATIER with other medicines.
If you take ZEPATIER with ribavirin, be sure you read the Medication Guide for ribavirin, especially the important pregnancy, contraception, and infertility information.
ZEPATIER may cause increases in your liver-related blood tests, which could be a sign of serious liver problems. Your health care provider will do blood tests to check your liver before and during treatment with ZEPATIER. Tell your health care provider right away if you get any of the following symptoms or if they get worse during treatment with ZEPATIER: loss of appetite, nausea and vomiting, feeling tired or weak, yellowing of your skin or eyes, or color changes in your stool.
In clinical studies, common side effects of ZEPATIER included: feeling tired, headache, and nausea. When ZEPATIER was taken with ribavirin, common side effects also included low red blood cell counts (called anemia).
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call
Please read the accompanying Patient Information for ZEPATIER and discuss it with your doctor. The physician Prescribing Information also is available.